Perfluoron in the anterior chamber (Video)

This video shows a perfluoron bubble sitting in the bottom of the eye in the anterior chamber. This chemical is used during retinal surgery to help lay down the retina. Here it has somehow gotten into the front portion of the eye. Since perfluorocarbon fluid is heavier than water, the bubble has sunken to the bottom of the chamber in front of the iris.

This foreign material needs to be watched closely as it can decompensate the cornea by killing the endothelial surface.

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perfluronbubble.wmv (3.3 meg, Windows video file)


Perfluoron Bubble
This photograph shows a perfluoron bubble sitting in the bottom of the anterior chamber of the eye.
Perfluoron is a wonderful tool for retinal detachment surgery. In this case, some managed to come forward into the AC. Hopefully, this cornea will not decompensate from endothelial cell loss.

Dr. Timothy Root is a practicing ophthalmologist and cataract surgeon in Daytona Beach, Florida. His books, video lectures, and training resources can be found at:


  1. how about the managment of this case

    Not much to manage … in that I’ve only seen this once. Elected to watch it periodically as the bubble was small and barely touching the cornea. If the cornea appeared to be suffering, then planning to take it out (possibly in the OR with a large bore canula?). Can’t find any publications describing this, so you have to wing it and see what works.


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