Vitamin supplementation has been found to be beneficial for people with macular degeneration. A large clinical trial called the AREDS Study was sponsored by the National Eye Institute. Its purpose was to look for supplements that might slow the progression of macular degeneration. They found that vitamins A, C, and E (along with the minerals zinc and copper) seemed to have a statistically significant benefit when ingested in high quantities. People with mild and moderate macular degeneration were 25% less likely to progress to advanced disease while on this vitamin cocktail, as compared to people taking a placebo. A follow-up AREDS 2 Study has found more supplements that might help, such as the plant pigments lutein and zeaxanthin. Eye vitamins are available over-the-counter and come in a slew of names and combinations. The most popular are Ocuvite, PreserVision, and I-Caps.