This is the latest study searching for additional supplements that slow down macular degeneration progression. In the original AREDS Study, researchers found that Vitamin A (beta-carotene), C, E and the metals zinc and copper were helpful in slowing the progression of vision loss. However, there are many more supplements out there that have been theorized to be healthy for the eye. The AREDS2 clinical trial finished in 2012 and the results are only now coming to light. It appears that the omega-3 fatty acids (DHA and EPA) had little effect on the eye, despite their known cardiac and stroke benefits. However, the plant pigments lutein and zeaxanthin were found to be helpful and may be a good replacement for beta-carotene (which is contraindicated in smokers because of increased lung cancer risk). AREDS 2 vitamins are beginning to show up on the shelves and are safe for most people. Vitamin packaging can be confusing. If you are a smoker or have had lung cancer, be sure to read the contents and avoid any vitamins with beta-carotene.