Alphagan P

This is a glaucoma eye drop designed to lower eye pressure. It is actually a “new” formulation of brimonidine that has a lower concentration of active drug and a less harsh preservative in it. Despite the decreased concentration, the drop appears to have the same efficacy as the old Alphagan but with less irritating side effects.

Dr. Timothy Root is a practicing ophthalmologist and cataract surgeon in Daytona Beach, Florida. His books, video lectures, and training resources can be found at:


  1. This medication is a remake of Alphagan (also known as Bromonidine). With this formulation, the company decreased the concentration of the drug from 0.15 percent down to 0.10 percent.

    This is supposed to decrease the side effects of the medication … mainly the eye redness that occurs with this glass of medications … while still maintaining the efficacy of the drop.

    I have no strong personal preference on these different formulations, and the formulation of brimonidine we end up using often ends up being determined by my patient’s drug coverage.


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